This webpage has brief information regarding bortezomib and a set of back links to more details about the use of this drug, exploration final results, and ongoing medical trials.

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Bortezomib sometimes will cause Unwanted side effects due to the speedy destruction of most cancers cells (tumor lysis syndrome). To reduce your risk, your doctor may perhaps incorporate a medication and show you to consume a good amount of fluids.

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explain to your health care provider and Health care supplier if you are allergic to bortezomib, mannitol, another drugs, boron, or any of the elements in bortezomib. Inquire your healthcare service provider for a summary of the elements.

larotrectinib will increase the amount or result of bortezomib AXL-IN-13 by 3'-cGAMP sodium influencing hepatic/intestinal enzyme CYP3A4 metabolism. Minimal/Importance Unidentified.

The pharmacist also needs to verify all dosing and consult with the ordering clinician regarding any discrepancies, together with carrying out comprehensive medication reconciliation. Right before dispensing the drug, the pharmacist need to ensure that the individual has no allergy symptoms and is labored up for tuberculosis and accomplish medication reconciliation. Also, the individual must obtain education and learning concerning the possible extensive-term adverse effects that could manifest, which includes neuropathy.

Determined by system of action and results in animals, drug may have an effect on possibly male or woman fertility

conivaptan will improve the stage or outcome of bortezomib by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep track of.

mifepristone will boost the level or outcome of bortezomib by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Watch.

phenytoin will lessen the level or result of bortezomib by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep track of.

Some Uncomfortable side effects may be serious. In case you working experience any of these indications, phone your physician promptly:

Hematological toxicity during a cycle: If extended Grade 4 neutropenia or thrombocytopenia, or thrombocytopenia with bleeding is noticed while in the earlier cycle, contemplate decreasing melphalan dose by twenty five% Lin281632 in the subsequent cycle